Ya, it does take a lot to run it. But miraculously the Compaq TC1000 TabletPC with Geforce2Go 100 GPU seems to run it adequately (along with other games like Jedi Knights II, Max Payne, and Freelancer).
I haven't played it yet, though. I hear that it's not as good as SimCity 3000. They changed a couple things which made the game harder or something like that

I don't know, I could never do well in SimCity3000 or 2000, so.... There was an old thread on this game created before it was released.