I probably should've said something a couple weeks back when I heard that some people were developing worms, but I forgot to mention it here. The first worms that exploit this hole are out, so if your running anything on the NT kernel, I highly suggest you find the patch. When hit, RPC is killed, and thus SYSTEM user shuts down. The patch is somewhere on MS, don't have the URL off hand.
BTW, if you happen to get hit, send me an IM or something, I've got the tool used to exploit it, working out a way to fix it remotely. I think if you can get the patch installed quick enough it'll work, once you are infected.
[edit] Apparently, if you can get the patch installed in 60 seconds, your good.
http://download.microsoft.com/download/ ... 86-ENU.exe
For XP Home. Find the page for other OSes
[edit2] Got any enemies? Send their IPs to me :P